About ePRaSE: Governance Structure

Governance & Clinical Assurance

ePRaSE is governed through a formal programme structure, with Programme Board oversight, defined workstreams, and clear accountability across NHS organisations.

Clinical content is developed and assured through Clinical Reference Groups (CRGs), comprising senior multidisciplinary experts who ensure clinical validity, safety relevance, and alignment to national priorities.

The Development & Assurance Process

  1. 01

    Research & Evidence

    Built initially from published literature, national safety data, and real prescribing risks.

  2. 02

    Expert Consensus

    Validated through a formal e-Delphi process, bringing together UK clinical experts to agree on high-risk scenarios.

  3. 03

    Scenario Development

    Translation of evidence into clinically realistic, high-risk prescribing tests.

  4. 04

    ePRaSE Tool

    Simulation platform using virtual patients to assess how systems respond to risk.

  5. 05

    NHS Deployment & Improvement

    Applied across organisations to identify variation, benchmark safety, and drive optimisation.

  6. 06

    Ongoing Expert Review

    Reviewed annually by a national network of clinical, academic, and patient safety experts to ensure:

    • Alignment with emerging risks and real-world practice
    • Incorporation of new safety issues, e.g., national safety alerts and evolving medicine uses
    • Reflection of current NHS priorities and clinical experience

Programme Structure & Workflow

ePRaSE Organisational Governance Structure
The Annual ePRaSE Evaluation Cycle
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